Publications and Posters

Exploring the Aβ plaque microenvironment in Alzheimer’s disease model mice by multimodal lipid-protein-histology imaging on a benchtop mass spectrometer
February 5, 2025  •  Müller, E., Enzlein, T., Niemeyer, D., von Ammon, L., Stumpo, K., Biber, K., Klein, C., & Hopf, C. (2025). Pharmaceuticals (Basel, Switzerland), 18(2), 252.
Exploring the Aβ Plaque Microenvironment in Alzheimer’s Disease Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer
December 7, 2024  •  Müller, E., Enzlein, T., Niemeyer, D., von Ammon, L., Stumpo, K., Biber, K., Klein, C., & Hopf, C. (2024). Cold Spring Harbor Laboratory. • Multiomic and Multimodal techniques
MALDI-IHC high-plex protein biomarker imaging for fast, non-iterative identification of lung carcinoma subtype
November 13, 2024  •  AACR 2024 • Catherine A. Kita, Leonardo G. Dettori, Kristina Schwamborn, Gargey Yagnik, Kenneth J. Rothschild, Mark J. Lim
Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson’s disease
September 18, 2024  •  Minnella, A., McCusker, K. P., Amagata, A., Trias, B., Weetall, M., Latham, J. C., O’Neill, S., Wyse, R. K., Klein, M. B., & Trimmer, J. K. (2024). In H. Nakano (Ed.), PLOS ONE (Vol. 19, Issue 9, p. e0309893). Public Library of Science (PLoS). • Drug study incorporating MALDI-IHC, Pharma
Multimodal Omics Imaging of Human Brain Using MALDI HiPLEX-IHC
June 2, 2024  •  ASMS 2024 • Yumiko Toyama, Takashi Nirasawa, Shigeo Murayama, Yuko Saito, Maho Morishima, Masaya Ikegawa
Cyclic MALDI-IHC for Successive High-plex and Multimodal Imaging of Tissues and Tissue Microarrays
June 2, 2024  •  ASMS 2024 • Leonardo G. Dettori, Gargey Yagnik, Philip Carvalho, Mark J. Lim and Kenneth J. Rothschild
Real-time glioblastoma tumor microenvironment assessment by SpiderMass for improved patient management
April 16, 2024  •  Zirem, Y., Ledoux, L., Roussel, L., Maurage, C. A., Tirilly, P., Le Rhun, É., Meresse, B., Yagnik, G., Lim, M. J., Rothschild, K. J., Duhamel, M., Salzet, M., & Fournier, I. (2024). In Cell Reports Medicine (Vol. 5, Issue 4, p. 101482). Elsevier BV. • MALDI-IHC was orthogonal verification tech
Abstract 7088: MALDI-IHC high-plex protein biomarker imaging for fast, non-iterative identification of lung carcinoma subtypes
March 15, 2024  •  Kita, C. A., Schwamborn, K., Yagnik, G., Rothschild, K. J., & Lim, M. J. (2024). In Cancer Research (Vol. 84, Issue 6_Supplement, pp. 7088–7088). American Association for Cancer Research (AACR). • Clinical Translation, Published Abstract
A novel 3D imaging method to establish baseline amyloid‐beta plaque load and analyze compound efficacy in pre‐clinical Alzheimer’s disease animal models
December 24, 2023  •  Ferron, G., Linehan, S. T., Ragan, T., Elk, K. J., Garceau, D., & Sasner, M. (2023). In Alzheimer’s & Dementia (Vol. 19, Issue S10). Wiley. • Published Abstract
The journey towards clinical adoption of MALDI-MS-based imaging proteomics: from current challenges to future expectations
December 23, 2023  •  Piga, I., Magni, F., & Smith, A. (2024). In FEBS Letters (Vol. 598, Issue 6, pp. 621–634). Wiley. • Clinical Translation, Review Article
MALDI HiPLEX-IHC: Highly Multiplex & Multiomic Tissue Imaging with Photocleavable Mass-Tagged Probes
June 5, 2022  •  ASMS 2022 • Gargey B. Yagnik; Ziying Liu; Zhi Wan; Kenneth J. Rothschild, Mark J. Lim