Publications and Posters

Exploring the Aβ plaque microenvironment in Alzheimer’s disease model mice by multimodal lipid-protein-histology imaging on a benchtop mass spectrometer
February 5, 2025  •  Müller, E., Enzlein, T., Niemeyer, D., von Ammon, L., Stumpo, K., Biber, K., Klein, C., & Hopf, C. (2025). Pharmaceuticals (Basel, Switzerland), 18(2), 252.
Exploring the Aβ Plaque Microenvironment in Alzheimer’s Disease Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer
December 7, 2024  •  Müller, E., Enzlein, T., Niemeyer, D., von Ammon, L., Stumpo, K., Biber, K., Klein, C., & Hopf, C. (2024). Cold Spring Harbor Laboratory. • Multiomic and Multimodal techniques
MALDI-IHC high-plex protein biomarker imaging for fast, non-iterative identification of lung carcinoma subtype
November 13, 2024  •  AACR 2024 • Catherine A. Kita, Leonardo G. Dettori, Kristina Schwamborn, Gargey Yagnik, Kenneth J. Rothschild, Mark J. Lim
Targeting ferroptosis with the lipoxygenase inhibitor PTC-041 as a therapeutic strategy for the treatment of Parkinson’s disease
September 18, 2024  •  Minnella, A., McCusker, K. P., Amagata, A., Trias, B., Weetall, M., Latham, J. C., O’Neill, S., Wyse, R. K., Klein, M. B., & Trimmer, J. K. (2024). In H. Nakano (Ed.), PLOS ONE (Vol. 19, Issue 9, p. e0309893). Public Library of Science (PLoS). • Drug study incorporating MALDI-IHC, Pharma
Multimodal Omics Imaging of Human Brain Using MALDI HiPLEX-IHC
June 2, 2024  •  ASMS 2024 • Yumiko Toyama, Takashi Nirasawa, Shigeo Murayama, Yuko Saito, Maho Morishima, Masaya Ikegawa
Cyclic MALDI-IHC for Successive High-plex and Multimodal Imaging of Tissues and Tissue Microarrays
June 2, 2024  •  ASMS 2024 • Leonardo G. Dettori, Gargey Yagnik, Philip Carvalho, Mark J. Lim and Kenneth J. Rothschild
A novel 3D imaging method to establish baseline amyloid‐beta plaque load and analyze compound efficacy in pre‐clinical Alzheimer’s disease animal models
December 24, 2023  •  Ferron, G., Linehan, S. T., Ragan, T., Elk, K. J., Garceau, D., & Sasner, M. (2023). In Alzheimer’s & Dementia (Vol. 19, Issue S10). Wiley. • Published Abstract
MALDI HiPLEX-IHC Imaging of FFPE Human Kidney Tissue at 5 µm utilizing microGRID on timsTOF fleX MALDI-2
June 4, 2023  •  ASMS 2023 • Connor West, Joshua Fischer, Corrina Henkel, Sumankalai Ramachandran, Azad Eshghi, Gargey Yagnik, Mark Lim
MALDI HiPLEX-IHC: Highly Multiplex & Multiomic Tissue Imaging with Photocleavable Mass-Tagged Probes
June 5, 2022  •  ASMS 2022 • Gargey B. Yagnik; Ziying Liu; Zhi Wan; Kenneth J. Rothschild, Mark J. Lim