Publications - AmberGen

Publications and Posters

A novel 3D imaging method to establish baseline amyloid‐beta plaque load and analyze compound efficacy in pre‐clinical Alzheimer’s disease animal models

December 24, 2023 • Ferron, G., Linehan, S. T., Ragan, T., Elk, K. J., Garceau, D., & Sasner, M. (2023). In Alzheimer’s & Dementia (Vol. 19, Issue S10). Wiley. • Published Abstract

The journey towards clinical adoption of MALDI-MS-based imaging proteomics: from current challenges to future expectations

December 23, 2023 • Piga, I., Magni, F., & Smith, A. (2024). In FEBS Letters (Vol. 598, Issue 6, pp. 621–634). Wiley. • Clinical Translation, Review Article

Deep MALDI-MS Spatial ‘Omics guided by Quantum Cascade Laser Mid-infrared Imaging Microscopy

December 14, 2023 • Gruber, L., Schmidt, S., Enzlein, T., Vo, H. G., Cairns, J. L., Ucal, Y., Keller, F., Abu Sammour, D., Rudolf, R., Eckhardt, M., Iakab, S. A., Bindila, L., & Hopf, C. (2023). Cold Spring Harbor Laboratory. • Multiomic and Multimodal techniques

Lipidomic Phenotyping Of Human Small Intestinal Organoids Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

December 7, 2023 • Duivenvoorden, A. A. M., Claes, B. S. R., van der Vloet, L., Lubbers, T., Glunde, K., Olde Damink, S. W. M., Heeren, R. M. A., & Lenaerts, K. (2023). In Analytical Chemistry (Vol. 95, Issue 50, pp. 18443–18450). American Chemical Society (ACS). • Multiomic, Organoids, Lipids, Proteins

A Guide to MALDI Imaging Mass Spectrometry for Tissues

October 25, 2023 • Jessica L. Moore, Georgia Charkoftaki. Journal of Proteome Research 2023, 22 (11) , 3401-3417. • Review Article

Combination of Multimodal Single Cell Imaging Methods with Multiplexed Enzyme-based MALDI-Mass Spectrometry Imaging for Translational Studies

October 23, 2023 • IMSIS 2023 • Jaclyn B. Dunne, Jake Griner, Martin Romeo, Carsten Krieg, Mark Lim, Gargey Yagnik Anand S. Mehta, Richard R. Drake, Peggi M. Angel

Evaluation of antibody-based single cell type imaging techniques coupled to multiplexed imaging of N-glycans and collagen peptides by matrix-assisted laser desorption/ionization mass spectrometry imaging

October 16, 2023 • Dunne, J., Griner, J., Romeo, M., Macdonald, J., Krieg, C., Lim, M., Yagnik, G., Rothschild, K. J., Drake, R. R., Mehta, A. S., & Angel, P. M. (2023). In Analytical and Bioanalytical Chemistry (Vol. 415, Issue 28, pp. 7011–7024). Springer Science and Business Media LLC. • Multiomic, Multimodal techniques

Towards Single-Cell MALDI HiPLEX-IHC: Multiplexed, Multiomic and Multimodal Imaging of Targeted Intact Proteins and Untargeted Metabolites

September 17, 2023 • HUPO 2023 • Mark Lim, Gargey Yagnik, Zhi Wan, Jonathan Bell, Joshua Fischer, Ethan Yang, Katherine A. Stumpo, Kenneth J. Rothschild

MALDI HiPLEX-IHC Imaging of FFPE Human Kidney Tissue at 5 µm utilizing microGRID on timsTOF fleX MALDI-2

June 4, 2023 • ASMS 2023 • Connor West, Joshua Fischer, Corrina Henkel, Sumankalai Ramachandran, Azad Eshghi, Gargey Yagnik, Mark Lim

Gel-assisted mass spectrometry imaging

June 3, 2023 • Chan, Y. H., Pathmasiri, K. C., Pierre-Jacques, D., Cologna, S. M., & Gao, R. (2023). Cold Spring Harbor Laboratory. • Multiomic and Multimodal techniques

MALDI HiPLEX-IHC: multiomic and multimodal imaging of targeted intact proteins in tissues

May 1, 2023 • Lim, M. J., Yagnik, G., Henkel, C., Frost, S. F., Bien, T., & Rothschild, K. J. (2023). In Frontiers in Chemistry (Vol. 11). Frontiers Media SA. • Multiomic and Multimodal techniques

MALDI-IHC-Guided In-Depth Spatial Proteomics: Targeted and Untargeted MSI Combined

January 13, 2023 • Claes, B. S. R., Krestensen, K. K., Yagnik, G., Grgic, A., Kuik, C., Lim, M. J., Rothschild, K. J., Vandenbosch, M., & Heeren, R. M. A. (2023). In Analytical Chemistry (Vol. 95, Issue 4, pp. 2329–2338). American Chemical Society (ACS). • Multimodal, proteins, lipids

MALDI-IHC-Guided In-Depth Spatial Proteomics

January 1, 2023 • B.S.R. Claes, K. K. Krestensen, G. Yagnik, A Grgic, C. Kuik, M.J. Lim , K.J. Rothschild, M. Vandenbosch, R.M.A. Heeren